The bioreaction can be coupled with different separation methods, such as gas stripping, solvent extraction, membrane separation, adsorption and ion-exchange, etc., to separate the product or by-product from reaction broth and to eliminate the inhibitory effect on the reaction. 生物反应可以与不同的分离方法(如气提、溶剂萃取、膜分离、吸附和离子交换等)耦合分离反应液中的产物和副产物以消除抑制效应。